Immunopathogenesis of Pulmonary Tuberculosis

Hosp Pract (Off Ed). 1993 Jan 15;28(1):51-8. doi: 10.1080/21548331.1993.11442738.

Abstract

Antimicrobial therapy quickly eradicates susceptible bacilli, but the fight against drug-resistant disease must be waged entirely by host defenses. Knowledge of the two main types of immune response against tuberculosis and of how to manipulate those mechanisms--leading to precisely designed recombinant BCG vaccines--is essential to mounting an effective attack on the current epidemic.

Publication types

  • Review

MeSH terms

  • Animals
  • Antitubercular Agents / pharmacology
  • Antitubercular Agents / therapeutic use
  • Disease Models, Animal
  • Humans
  • Immunity, Cellular / immunology*
  • Rabbits
  • Severity of Illness Index
  • T-Lymphocytes / immunology
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / immunology*
  • Tuberculosis, Pulmonary / pathology

Substances

  • Antitubercular Agents