Outpatient management with oral corticosteroid therapy for obstructive conditions in chronic granulomatous disease

J Pediatr. 1993 Feb;122(2):303-5. doi: 10.1016/s0022-3476(06)80138-1.


We report the outpatient management of three patients with X-linked chronic granulomatous disease, two of whom had episodes of gastric outlet obstruction and another, urinary bladder obstruction. These obstructive conditions were successfully treated with 2-week courses of orally administered corticosteroids with or without the addition of orally administered clindamycin. There were no infectious or other adverse reactions.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Ambulatory Care
  • Child
  • Clindamycin / administration & dosage
  • Clindamycin / therapeutic use
  • Gastric Outlet Obstruction / drug therapy*
  • Granulomatous Disease, Chronic / drug therapy*
  • Humans
  • Male
  • Prednisone / administration & dosage
  • Prednisone / therapeutic use*
  • Recurrence
  • Urinary Bladder Neck Obstruction / drug therapy*


  • Clindamycin
  • Prednisone