Review of the tear break-up time and a closer look at the tear break-up time of Hong Kong Chinese

Optom Vis Sci. 1993 Jan;70(1):30-8. doi: 10.1097/00006324-199301000-00007.


The technique of assessing tear stability using the fluorescein instillation technique has been widely used in the clinical diagnosis of "dry eye" and in the screening of potential contact lens wearers. Various inconsistencies in the application of the tear break-up time (TBUT) techniques and the results obtained were noted in the literature and this review summarizes the differences and the conclusions of various investigators. The reliability of this technique using two different methods of observation was examined and the mean TBUT of Hong Kong Chinese subjects (HK-Chinese) was determined. We conclude that the TBUT can be measured reliably using either the scanning or full beam method in most patients. The mean TBUT of HK-Chinese is approximately 8 s and about 70% of HK-Chinese have TBUT's less than 10 s.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Fluorescein
  • Fluoresceins / pharmacology
  • Humans
  • Male
  • Middle Aged
  • Ophthalmology / methods
  • Reproducibility of Results
  • Tears / drug effects
  • Tears / physiology*


  • Fluoresceins
  • Fluorescein