Evolution of Salmonella O antigen variation by interspecific gene transfer on a large scale

Trends Genet. 1993 Jan;9(1):17-22. doi: 10.1016/0168-9525(93)90067-R.


The O antigen is a bacterial surface polysaccharide made up of repeats of a short oligosaccharide. There are about 60 forms of O antigen in Salmonella, and genetic analysis indicates that these were acquired by interspecific gene transfer.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antigenic Variation / genetics*
  • Antigens, Bacterial / chemistry
  • Antigens, Bacterial / genetics*
  • Carbohydrate Sequence
  • Genes, Bacterial
  • Molecular Sequence Data
  • Multigene Family
  • Polymorphism, Genetic*
  • Salmonella / genetics
  • Salmonella / immunology*
  • Sequence Homology, Amino Acid
  • Transfection*


  • Antigens, Bacterial