The isolation of cytotoxic necrotizing factor (CNF)-producing Escherichia coli from the intestinal contents of babies who died of sudden infant death syndrome (SIDS) and other causes as well as from the faeces of healthy babies

Comp Immunol Microbiol Infect Dis. 1993 Jan;16(1):87-90. doi: 10.1016/0147-9571(93)90065-d.

Abstract

Strains of Escherichia coli producing cytotoxic necrotizing factor (CNF) have been isolated from intestinal contents of 16.8% of babies who died of Sudden Infant Death Syndrome (SIDS) and 16.5% of faeces from healthy babies. While no difference in CNF carriage was seen, it is noteworthy that these CNF-producing E. coli are present in such specimens. Some of the CNF-producing E. coli belonged to serotypes associated with this factor in other parts of the world.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Toxins / biosynthesis*
  • Carrier State / microbiology
  • Cytotoxins / biosynthesis*
  • Escherichia coli / isolation & purification*
  • Escherichia coli / metabolism
  • Escherichia coli / pathogenicity
  • Escherichia coli Infections / complications
  • Escherichia coli Infections / microbiology
  • Escherichia coli Proteins*
  • Feces / microbiology
  • Humans
  • Infant
  • Intestines / microbiology*
  • Sudden Infant Death / etiology*

Substances

  • Bacterial Toxins
  • Cytotoxins
  • Escherichia coli Proteins
  • cytotoxic necrotizing factor type 1