Environmental strains of Enterococcus faecium with inducible high-level resistance to glycopeptides

FEMS Microbiol Lett. 1993 Jan 1;106(1):23-9. doi: 10.1111/j.1574-6968.1993.tb05930.x.


High-level resistance to glycopeptides in Enterococcus faecium is associated with an inducible 39-kDa cytoplasmic membrane protein. The present paper shows that such glycopeptide-resistant E. faecium strains can not only be isolated in a definite clinical setting but also from waste water of sewage treatment plants. Nearer characterization of these and of clinical isolates by resistance pattern, biotyping, and genotyping (DNA-fingerprinting with pulsed-field gel electrophoresis) has shown that different glycopeptide-resistant E. faecium strains have been isolated from clinical sources and from waste water.

MeSH terms

  • DNA Fingerprinting
  • Drug Resistance, Microbial*
  • Enterococcus faecium / classification
  • Enterococcus faecium / drug effects
  • Enterococcus faecium / genetics
  • Enterococcus faecium / isolation & purification*
  • Glycopeptides / pharmacology
  • Medical Waste
  • Sewage*


  • Glycopeptides
  • Medical Waste
  • Sewage