A new pair of surface molecules involved in human IgE regulation

J Y Bonnefoy; S Pochon; J P Aubry; P Graber; J F Gauchat; K Jansen; L Flores-Romo

doi:10.1016/0167-5699(93)90313-A

A new pair of surface molecules involved in human IgE regulation

Immunol Today. 1993 Jan;14(1):1-2. doi: 10.1016/0167-5699(93)90313-A.

Authors

J Y Bonnefoy¹, S Pochon, J P Aubry, P Graber, J F Gauchat, K Jansen, L Flores-Romo

Affiliation

¹ Glaxo Institute for Molecular Biology, Ouates/Geneva, Switzerland.

PMID: 8442854
DOI: 10.1016/0167-5699(93)90313-A

Abstract

The molecules controlling IgE production are the subject of intense study in the effort to find new ways to treat allergic diseases. One candidate, the CD23 molecule, a low affinity receptor for IgE, was recently identified to interact with another molecule, named CD21, in the regulation of IgE production.

Publication types

Review

MeSH terms

B-Lymphocytes / immunology
Humans
Immunoglobulin E / biosynthesis*
Interleukin-4 / pharmacology
Receptors, Complement 3d / metabolism
Receptors, IgE / metabolism

Substances

Receptors, Complement 3d
Receptors, IgE
Interleukin-4
Immunoglobulin E