Intrathecal baclofen in severe spasticity

Br J Hosp Med. 1993 Feb 17-Mar 2;49(4):262-7.

Abstract

Control of severe spasticity and its associated features with administration of baclofen directly into the CSF via an intrathecal pump has radically improved the management of patients resistant to oral therapy. This article reviews the rationale and clinical indications for this technique, and the outcome and complications encountered.

Publication types

  • Review

MeSH terms

  • Baclofen / administration & dosage*
  • Baclofen / pharmacology
  • Baclofen / therapeutic use
  • Clinical Protocols / standards
  • Clinical Trials as Topic
  • Electric Stimulation Therapy / methods
  • Humans
  • Infusion Pumps, Implantable
  • Injections, Spinal
  • Muscle Spasticity / diagnosis
  • Muscle Spasticity / drug therapy*
  • Muscle Spasticity / surgery
  • Nerve Block / methods
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Baclofen