Mitomycin as adjunct therapy in correcting iatrogenic punctal stenosis

Ophthalmic Surg. 1993 Feb;24(2):123-4.


A 52-year-old woman developed persistent epiphora in her left eye after undergoing occlusion of the left puncta. Two attempts to reopen the puncta with a one-snip procedure and placement of punctal silicone plugs failed. The epiphora resolved and the puncta remained patent after the patient underwent a third one-snip procedure, supplemented with topical mitomycin during and after surgery.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Chemotherapy, Adjuvant
  • Dacryocystorhinostomy*
  • Female
  • Humans
  • Iatrogenic Disease
  • Lacrimal Apparatus Diseases / etiology
  • Lacrimal Duct Obstruction / complications
  • Lacrimal Duct Obstruction / drug therapy
  • Middle Aged
  • Mitomycins / therapeutic use*


  • Mitomycins