Running-induced alterations in growth hormone, prolactin, triiodothyronine, and thyroxine concentrations in trained and untrained men and women

Res Q Exerc Sport. 1993 Mar;64(1):69-74. doi: 10.1080/02701367.1993.10608780.


This study examined whether gender and/or training were related to the exercise-induced changes in plasma concentrations of growth hormone (GH), prolactin (PRL), triiodothyronine (T3), and thyroxine (T4). Twenty subjects (male and female 10-km runners; untrained males and females) ran on a treadmill for 30 min at 80% of previously determined maximum heart rate. Blood samples were taken through an indwelling catheter from an antecubital vein at -30, 0, +15, +30 min of the test and 30 min of recovery. Rectal temperature rose significantly (p < .01) at +15 and +30 min with concomitant rise in GH concentration, but PRL, T3, and T4 were not affected by the exercise. We concluded that a 30-min run at 80% of maximum heart rate is associated with higher concentrations of GH but not of PRL, T3, and T4. Neither training state nor gender affected the aforementioned results.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Growth Hormone / blood*
  • Heart Rate / physiology
  • Humans
  • Male
  • Physical Education and Training
  • Prolactin / blood*
  • Running / physiology*
  • Sex Factors
  • Thyroxine / blood*
  • Triiodothyronine / blood*


  • Triiodothyronine
  • Prolactin
  • Growth Hormone
  • Thyroxine