Comparative toxicity and pathology associated with administration of recombinant IL-2 to animals

Int Rev Exp Pathol. 1993;34 Pt A:57-77.
No abstract available

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Anemia, Hemolytic / chemically induced
  • Anemia, Hemolytic / pathology
  • Animals
  • Chemical and Drug Induced Liver Injury / etiology
  • Female
  • G(M1) Ganglioside / immunology
  • Hepatomegaly / chemically induced
  • Hepatomegaly / pathology
  • Immunization, Passive
  • Inflammation / chemically induced
  • Inflammation / pathology
  • Interleukin-2 / administration & dosage
  • Interleukin-2 / toxicity*
  • Killer Cells, Lymphokine-Activated / drug effects
  • Killer Cells, Lymphokine-Activated / pathology
  • Macaca fascicularis
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, SCID
  • Pulmonary Edema / chemically induced
  • Pulmonary Edema / pathology
  • Pulmonary Eosinophilia / chemically induced
  • Pulmonary Eosinophilia / pathology
  • Rats
  • Receptors, Interleukin-1 / immunology
  • Recombinant Proteins / administration & dosage
  • Recombinant Proteins / toxicity
  • Severe Combined Immunodeficiency / therapy
  • Splenomegaly / chemically induced
  • Splenomegaly / pathology
  • Tumor Necrosis Factor-alpha / immunology
  • Viscera / pathology

Substances

  • Interleukin-2
  • Receptors, Interleukin-1
  • Recombinant Proteins
  • Tumor Necrosis Factor-alpha
  • G(M1) Ganglioside
  • asialo GM1 ganglioside