Empiric antibiotic therapy of abdominal sepsis and serious perioperative infections

Surg Clin North Am. 1993 Apr;73(2):291-306. doi: 10.1016/s0039-6109(16)45982-7.


This article discusses empiric therapy for several serious infections in surgical patients. The accepted antibiotic treatment for purulent peritonitis, the empiric treatment of postsurgical wound infection, and the empiric treatment of postsurgical pneumonia are discussed. The cost of the various regimens is listed. Recommendation of the various regimens is based on the seriousness of the infection, peculiarities of the hospital flora, effectiveness of the regimens, and cost.

Publication types

  • Review

MeSH terms

  • Aminoglycosides
  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / drug therapy*
  • Cross Infection / etiology
  • Drug Therapy, Combination
  • Humans
  • Peritonitis / drug therapy*
  • Peritonitis / microbiology
  • Pneumonia / drug therapy*
  • Pneumonia / microbiology
  • Postoperative Complications / drug therapy*
  • Surgical Wound Infection / drug therapy*


  • Aminoglycosides
  • Anti-Bacterial Agents