Synthesis of low-toxicity, 5-deoxy-5-fluoro and 5-deoxy-5,5-difluoro derivatives of arbekacin and its analogs, and study of structure-toxicity relationships

Carbohydr Res. 1993 Feb 24:240:307-12. doi: 10.1016/0008-6215(93)84194-b.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Aminoglycosides*
  • Animals
  • Anti-Bacterial Agents*
  • Deoxy Sugars / chemistry
  • Dibekacin / analogs & derivatives*
  • Dibekacin / chemistry
  • Dibekacin / toxicity
  • Fluorine / chemistry
  • Lethal Dose 50
  • Mice
  • Mice, Inbred ICR
  • Microbial Sensitivity Tests
  • Structure-Activity Relationship

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • Deoxy Sugars
  • Fluorine
  • Dibekacin
  • arbekacin