Ozone: A Possible Cause of Hemolytic Anemia in glucose-6-phosphate Dehydrogenase Deficient Individuals

J Toxicol Environ Health. 1977 Jan;2(3):709-12. doi: 10.1080/15287397709529470.

Abstract

A theoretical model is described that predicts that individuals with a glucose-6-phosphate dehydrogenase deficiency may experience acute hemolysis on exposure to ozone at levels reached in certain urban centers.

MeSH terms

  • Adult
  • African Continental Ancestry Group
  • Anemia, Hemolytic / chemically induced*
  • Female
  • Glucosephosphate Dehydrogenase / blood
  • Glucosephosphate Dehydrogenase Deficiency / complications*
  • Glutathione / blood
  • Hemolysis / drug effects
  • Humans
  • Male
  • Oxidation-Reduction
  • Ozone / toxicity*

Substances

  • Ozone
  • Glucosephosphate Dehydrogenase
  • Glutathione