Dolphin and Porpoise Morbilliviruses Are Genetically Distinct From Phocine Distemper Virus

Virology. 1993 Apr;193(2):1010-2. doi: 10.1006/viro.1993.1217.

Abstract

The morbilliviruses recently isolated from two cetacean species in the North and Mediterranean Seas have been shown to differ from phocine distemper virus isolated from European seals using monoclonal antibodies. We have identified a "universal" morbillivirus primer set, based on highly conserved regions of the morbillivirus phosphoprotein (P) gene and used this to amplify a region surrounding the RNA editing site from all known members of the group. Sequence analysis of this region of the gene shows that the dolphin and porpoise viruses are related but quite different from all other members of the group, forming a distinct lineage more closely related to the ruminant morbilliviruses than to the carnivore viruses.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • DNA, Viral / genetics
  • Dolphins / microbiology*
  • Measles virus / classification*
  • Measles virus / genetics
  • Measles virus / isolation & purification
  • Molecular Sequence Data
  • Oligodeoxyribonucleotides
  • Phylogeny*
  • Polymerase Chain Reaction / methods
  • Seals, Earless / microbiology*
  • Sequence Homology, Nucleic Acid

Substances

  • DNA, Viral
  • Oligodeoxyribonucleotides

Associated data

  • GENBANK/K01711
  • GENBANK/M32418
  • GENBANK/X65512
  • GENBANK/X68311