Chronic granulomatous anterior uveitis associated with multiple sclerosis

Graefes Arch Clin Exp Ophthalmol. 1993 Mar;231(3):166-8. doi: 10.1007/BF00920941.


A retrospective review is presented of the medical records of seven female patients with uveitis associated with definite multiple sclerosis. Six of the patients had severe bilateral chronic granulomatous anterior uveitis, which in four cases resulted in extensive posterior synechiae and scarring of the peripupillary iris. One patient had bilateral intermediate uveitis with unilateral posterior synechiae. Severe chronic granulomatous anterior uveitis associated with multiple sclerosis has a predilection for women, can precede neurological symptoms and can be controlled with topical steroids.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Topical
  • Anti-Inflammatory Agents / therapeutic use
  • Chronic Disease
  • Female
  • Follow-Up Studies
  • Glucocorticoids
  • Granuloma / complications*
  • Granuloma / drug therapy
  • Humans
  • Multiple Sclerosis / complications*
  • Multiple Sclerosis / drug therapy
  • Retrospective Studies
  • Uveitis, Anterior / complications*
  • Uveitis, Anterior / drug therapy
  • Uveitis, Intermediate / complications
  • Uveitis, Intermediate / drug therapy


  • Anti-Inflammatory Agents
  • Glucocorticoids