Nephrocalcinosis in Very Low Birth Weight Neonates: Family History of Kidney Stones and Ethnicity as Independent Risk Factors

J Pediatr. 1993 Apr;122(4):635-8. doi: 10.1016/s0022-3476(05)83553-x.

Abstract

Serial renal ultrasonography was performed in 50 consecutive neonates with birth weights less than 1200 gm who survived to at least 3 weeks of age. Nephrocalcinosis developed in 8 (67%) of 12 white and only 6 (16%) of 38 nonwhite infants (p < 0.01). Seven (78%) of nine infants with a family history of kidney stones had nephrocalcinosis compared with only 7 (17%) of 41 without a family history of kidney stones (p < 0.001). We conclude that nephrocalcinosis in our population of very low birth weight neonates is significantly and independently associated with a family history of kidney stones and white race.

Publication types

  • Comparative Study

MeSH terms

  • Birth Weight
  • European Continental Ancestry Group
  • Female
  • Humans
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Infant, Premature, Diseases / diagnostic imaging
  • Infant, Premature, Diseases / epidemiology*
  • Infant, Premature, Diseases / genetics
  • Kidney / diagnostic imaging
  • Kidney Calculi / genetics*
  • Male
  • Nephrocalcinosis / diagnostic imaging
  • Nephrocalcinosis / epidemiology*
  • Nephrocalcinosis / genetics
  • Risk Factors
  • Ultrasonography