[The radioprotective action of an extract of regenerating spleen]

Radiobiologiia. 1993 Jan-Feb;33(1):141-7.
[Article in Russian]

Abstract

An extract from regenerating calf spleen increases the survival rate of mice when injected after irradiation. The studies of the blood and immune systems characteristics at the subcellular, cellular and tissue levels have been shown that the preparation containing a complex of hemoregulating compounds modifies the processes responsible for radiation damage and repair.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Animals
  • Antibody-Producing Cells / drug effects
  • Bone Marrow / drug effects
  • Bone Marrow / radiation effects
  • Bone Marrow Cells
  • Cattle
  • Drug Evaluation, Preclinical
  • Hematopoietic Stem Cells / drug effects
  • Mice
  • Mice, Inbred AKR
  • Mice, Inbred C57BL
  • Radiation Injuries, Experimental / mortality
  • Radiation Injuries, Experimental / prevention & control
  • Radiation-Protective Agents / pharmacology
  • Radiation-Protective Agents / therapeutic use*
  • Regeneration*
  • Spleen / physiology*
  • Time Factors
  • Tissue Extracts / pharmacology
  • Tissue Extracts / therapeutic use*

Substances

  • Radiation-Protective Agents
  • Tissue Extracts