Concomitant coronary revascularization and resection of lung cancer

Aust N Z J Surg. 1993 May;63(5):336-40. doi: 10.1111/j.1445-2197.1993.tb00398.x.

Abstract

As age and smoking are common risk factors, patients with lung cancer frequently have coexistent ischaemic heart disease. Ignoring the coronary disease results in an unacceptable operative mortality, whilst sequential coronary grafting and lung resection may prejudice the results of the resection. A series of 10 patients underwent combined coronary revascularization (average 2.9 grafts per patient) and lung resection for carcinoma (seven lobectomies, one bilobectomy, one sleeve lobectomy, and one pneumonectomy). The majority of patients had unstable angina, triple vessel or left main coronary artery stenosis and poorly staged tumours. There was no operative mortality and the average hospital stay was 20 days. Half the patients had significant peri-operative morbidity; seven are alive and well at between 12 and 38 months follow-up; but three have died of recurrent carcinoma (one with associated sepsis) at 3, 8, and 13 months. Combined coronary revascularization and lung resection can be safely performed in selected patients. The early morbidity is mainly related to the cardiac procedure and impaired respiratory function preoperatively, but the long-term results are dependent upon the control of the lung carcinoma.

MeSH terms

  • Adenocarcinoma / complications
  • Adenocarcinoma / surgery*
  • Aged
  • Carcinoma, Squamous Cell / complications
  • Carcinoma, Squamous Cell / surgery*
  • Coronary Disease / complications
  • Coronary Disease / surgery*
  • Female
  • Humans
  • Lung Neoplasms / complications
  • Lung Neoplasms / surgery*
  • Male
  • Middle Aged
  • Myocardial Revascularization*