Comparison of taurine, alpha-tocopherol, retinol, selenium, and total triglycerides and cholesterol concentrations in cats with cardiac disease and in healthy cats

Am J Vet Res. 1993 Apr;54(4):563-9.

Abstract

Epidemiologic relations were evaluated between plasma concentrations of nutrients and cardiovascular diseases. A total of 220 cats were assessed: 144 cats with noninduced acquired heart disease and 76 clinically normal cats. Plasma was assayed for taurine, alpha-tocopherol, selenium, retinol, and total cholesterol and triglycerides concentrations. Cardiovascular disease groups included dilated cardiomyopathy (n = 53), left ventricular hypertrophy (n = 28), hyperthyroidism (n = 11), and uncertain classification (n = 52). In cats with dilated cardiomyopathy, mean plasma taurine concentration was the lowest of that in cats of any group, being only 38% of the value in healthy cats; females had less than half the mean value of males. Tocopherol concentration was 20% lower than normal, and retinol concentration was 40% higher than normal. Total cholesterol concentration was 36% lower than normal. Triglycerides concentration was higher in these cats than in any other group--twice the value recorded in healthy cats and 67% higher than that in hyperthyroid cats. In cats with hypertrophic cardiomyopathy, almost 15% had mean plasma taurine concentration < 30 mumol/L. Retinol concentration was 15% higher, and triglycerides concentration was 54% higher than normal. Approximately 27% of hyperthyroid cats had mildly decreased plasma taurine concentration. Hyperthyroid cats had the lowest tocopherol and cholesterol values; both were at least 30% lower than normal. Retinol concentration was 30% higher than normal. Approximately 14% of cats with uncertain classification had mildly decreased plasma taurine concentration. Plasma retinol and triglycerides concentrations were higher than normal in 25 and 38% of these cats, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cardiomyopathy, Dilated / blood
  • Cardiomyopathy, Dilated / veterinary
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / veterinary*
  • Cat Diseases / blood*
  • Cats / blood*
  • Cholesterol / blood
  • Female
  • Hyperthyroidism / blood
  • Hyperthyroidism / veterinary
  • Hypertrophy, Left Ventricular / blood
  • Hypertrophy, Left Ventricular / veterinary
  • Male
  • Reference Values
  • Selenium / blood
  • Sex Factors
  • Taurine / blood
  • Triglycerides / blood
  • Vitamin A / blood
  • Vitamin E / blood

Substances

  • Triglycerides
  • Vitamin A
  • Vitamin E
  • Taurine
  • Cholesterol
  • Selenium