Effects of sedation and supplemental oxygen during upper alimentary tract endoscopy

Scand J Gastroenterol. 1993 Apr;28(4):319-22. doi: 10.3109/00365529309090249.


The effects of supplemental oxygen therapy on arterial oxygen saturation (SaO2) in unsedated and sedated patients have been studied using pulse oximetry. Hypoxia (minimum SaO2 92% or less) occurred in 41% of unsedated patients breathing room air but in only 11% (p < 0.01) of those receiving supplemental oxygen (41/min) by nasal cannulae. Comparable effects were seen in sedated patients (60% versus 16%, respectively, p < 0.01). Hypoxia during upper alimentary tract endoscopy is common with or without sedation and can be reduced by supplemental oxygen.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Conscious Sedation*
  • Diazepam
  • Endoscopy, Digestive System*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Oxygen / administration & dosage*
  • Oxygen / blood


  • Diazepam
  • Oxygen