Extravasation of contrast medium from the lenticulostriate artery following local intracarotid fibrinolysis

Surg Neurol. 1993 Apr;39(4):315-9. doi: 10.1016/0090-3019(93)90013-q.


Two patients with acute embolic occlusion of the intracranial internal carotid artery and the lenticulostriate arteries were treated by local intraarterial fibrinolysis using tissue plasminogen activator. Although fibrinolysis started within 2.5 hours from the ictus, extravasation of the contrast medium from the lenticulostriate arteries occurred in the region of the basal ganglia. Local intraarterial fibrinolysis for acute embolic occlusion of the internal carotid artery may be a high-risk therapeutic intervention even within the ultra-acute stage, especially when the lenticulostriate arteries are occluded by an embolus.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carotid Artery Thrombosis / therapy*
  • Carotid Artery, Internal
  • Cerebral Angiography
  • Cerebral Arteries
  • Extravasation of Diagnostic and Therapeutic Materials / etiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Thrombolytic Therapy / adverse effects*
  • Tomography, X-Ray Computed