Case of (Y;1) familial translocation

Am J Med Genet. 1993 May 15;46(3):339-40. doi: 10.1002/ajmg.1320460319.


A balanced reciprocal translocation t(1;Y) (q11;q11) was found in an infertile man with severe oligoasthenospermia. The same translocation was found in his father. The role of X-chromosome inactivation during meiosis in a male carrying a Y;autosome translocation is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chromosome Banding
  • Chromosomes, Human, Pair 1*
  • Dosage Compensation, Genetic
  • Humans
  • Infertility, Male / genetics*
  • Karyotyping
  • Male
  • Oligospermia / genetics*
  • Translocation, Genetic*
  • Y Chromosome*