In situ hybridization. A research technique or routine diagnostic test?

Arch Pathol Lab Med. 1993 May;117(5):478-81.


In situ hybridization is the molecular method for localizing nucleic acid targets in the context of histomorphology. As such, it has tremendous potential application in research and diagnostic pathology. This essay attempts to briefly review the in situ method and to clarify its position as an emerging clinically useful technology.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Diagnostic Tests, Routine / methods*
  • Humans
  • In Situ Hybridization*
  • Research Design*