The comprehensive assessment of health status in survivors of childhood cancer: application to high-risk acute lymphoblastic leukaemia

Br J Cancer. 1993 May;67(5):1047-52. doi: 10.1038/bjc.1993.192.


The health status of 69 survivors of high-risk acute lymphoblastic leukaemia (ALL) is assessed using a multi-attribute classification system. Seven attributes are included: sensation, mobility, emotion, cognition, self-care, pain and fertility. Three to five levels of functioning are defined for each attribute. Comprehensive health states are described as a specific combination of seven attribute levels. The system captures combinations of sequelae. The system provides a compact but comprehensive tool for long term follow up of survivors of childhood cancer. The results underscore the cognitive and emotional burdens of morbidity affecting survivors of high-risk ALL.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cognition Disorders / etiology
  • Female
  • Humans
  • Infertility / etiology
  • Male
  • Outcome Assessment, Health Care
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / physiopathology*
  • Survival Rate