Multizone PRK has been suggested to increase the predictability of higher myopic corrections. The technique consists of dividing the intended correction between two or three different concentric ablation zones, achieving less depth and a smoother ablation profile. We randomized 24 eyes with refractions between -6.00 and -9.00 D for single or double ablation-zone PRK. At 1 year no significant difference in refraction and complications were found between the two treatments. The multizone PRK technique may be safely employed to reduce the maximum central depth of the keratectomy in high myopics.