In situ hybridization localizes the human OTF3 to chromosome 6p21.3-->p22 and OTF3L to 12p13

Cytogenet Cell Genet. 1993;63(4):212-4. doi: 10.1159/000133537.


Otf-3 (Octamer-binding transcription factor 3) is an octamer binding protein encoded by the murine gene Otf-3. Otf-3 belongs to a multigenic family and maps to the mouse Chromosome 17 between the Q and T regions within the major histocompatibility complex (MHC). We report the mapping of the human homologue: OTF3, to human chromosome 6p21.3-->p22 within or close to the human MHC class I region. Furthermore, one OTF3-like copy (OTF3L) is localized to 12p13.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azure Stains
  • Chromosome Banding
  • Chromosome Mapping / methods
  • Chromosomes, Human, Pair 12*
  • Chromosomes, Human, Pair 6*
  • DNA-Binding Proteins / genetics*
  • Genes, MHC Class I
  • Humans
  • In Situ Hybridization
  • Octamer Transcription Factor-3
  • Transcription Factors / genetics*


  • Azure Stains
  • DNA-Binding Proteins
  • Octamer Transcription Factor-3
  • POU5F1 protein, human
  • Transcription Factors