Scleroderma and autoimmune thrombocytopenia associated with ingestion of L-tryptophan

Br J Dermatol. 1993 May;128(5):581-3. doi: 10.1111/j.1365-2133.1993.tb00241.x.

Abstract

We report the occurrence of scleroderma and autoimmune thrombocytopenia in a patient who took L-tryptophan as a muscle-building adjuvant. This is the first time such an association has been reported.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Antinuclear / analysis
  • Autoantibodies / analysis
  • Autoimmune Diseases / chemically induced*
  • Autoimmune Diseases / drug therapy
  • Azathioprine / therapeutic use
  • Drug Therapy, Combination
  • Humans
  • Male
  • Prednisolone / therapeutic use
  • Scleroderma, Localized / chemically induced*
  • Scleroderma, Localized / drug therapy
  • Thrombocytopenia / chemically induced*
  • Thrombocytopenia / drug therapy
  • Tryptophan / adverse effects*

Substances

  • Antibodies, Antinuclear
  • Autoantibodies
  • Tryptophan
  • Prednisolone
  • Azathioprine