Postkeratoplasty astigmatism with single running suture or interrupted sutures

Am J Ophthalmol. 1993 Jun 15;115(6):715-21. doi: 10.1016/s0002-9394(14)73637-2.


In a prospective randomized clinical trial we compared astigmatism after penetrating keratoplasty with two different suture techniques between two groups of patients (38 patients). The first group (18 patients) had a 24-bite single running 10-0 nylon suture (single running suture) with postoperative suture adjustment to decrease astigmatism. The second group (20 patients) had a combination of a 16-bite running 10-0 nylon suture and eight interrupted 10-0 nylon sutures (combined running and interrupted sutures) with selective postoperative removal of interrupted sutures to decrease astigmatism. The single running suture resulted in a lower postoperative astigmatism than a combined running and interrupted suture technique (single running suture, 2.7 +/- 2.2 diopters; combined running and interrupted sutures, 3.9 +/- 2.5 diopters; P < .02). Average length of follow-up was similar in both groups (single running suture, 9.0 +/- 2.2 months and combined running and interrupted sutures, 8.4 +/- 2.2 months). Minimal length of follow-up was six months in both groups. No running sutures were broken. The adjustable single running suture technique provided greater control of astigmatism after penetrating keratoplasty than a technique using a combination of a 16-bite running suture and eight interrupted sutures.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Astigmatism / etiology
  • Astigmatism / prevention & control*
  • Corneal Diseases / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Keratoplasty, Penetrating / adverse effects*
  • Male
  • Middle Aged
  • Nylons
  • Prognosis
  • Prospective Studies
  • Suture Techniques*
  • Sutures


  • Nylons