Targets of cyclin-dependent protein kinases

Curr Opin Cell Biol. 1993 Apr;5(2):187-93. doi: 10.1016/0955-0674(93)90101-u.

Abstract

Our current understanding of the eukaryotic cell cycle attributes a key regulatory role to cyclin-dependent protein kinases. It is important, therefore, to identify the physiological substrates of these kinases, and to understand how the phosphorylation of such proteins promotes cell cycle progression.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Cycle*
  • Cyclins*
  • DNA Replication
  • Humans
  • Multienzyme Complexes
  • Protein Kinases*

Substances

  • Cyclins
  • Multienzyme Complexes
  • Protein Kinases