The multifunctional Ca2+/calmodulin-dependent protein kinases

Curr Opin Cell Biol. 1993 Apr;5(2):247-53. doi: 10.1016/0955-0674(93)90111-3.

Abstract

Ca2+ mediates the effect of many hormones, neurotransmitters and growth factors on contractility and motility, carbohydrate metabolism, cell cycle, gene expression and neuronal plasticity. Multifunctional Ca2+/calmodulin-dependent (CaM) kinase, CaM kinase Ia, CaM kinase Ib and CaM kinase IV are four of the kinases that mediate Ca(2+)-signaling pathways. Recent studies have clarified our understanding of their structure, regulation and function.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Calcium / metabolism
  • Calcium-Calmodulin-Dependent Protein Kinase Type 4
  • Calcium-Calmodulin-Dependent Protein Kinases*
  • Models, Biological
  • Molecular Sequence Data
  • Multienzyme Complexes
  • Phosphorylation
  • Protein Kinases*

Substances

  • Multienzyme Complexes
  • Protein Kinases
  • Calcium-Calmodulin-Dependent Protein Kinase Type 4
  • Calcium-Calmodulin-Dependent Protein Kinases
  • Calcium