Similarity of DNA fingerprints due to chance and relatedness

Hum Hered. Jan-Feb 1993;43(1):45-52. doi: 10.1159/000154113.

Abstract

Given the DNA fingerprints of two individuals with some bands being shared by both individuals, we define a new measure of the degree of similarity between the DNA profiles of two individuals. We use this measure to calculate the expected DNA similarity of two unrelated individuals of a randomly mating population; this similarity is due to chance only. Then, the expected similarity between two related individuals is obtained; this similarity is due to chance and relatedness. From these results, the degree of similarity due to relatedness alone may be calculated.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alleles
  • DNA Fingerprinting*
  • Family
  • Humans
  • Probability