A motility in the eukaryotic flagellum unrelated to flagellar beating

Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5519-23. doi: 10.1073/pnas.90.12.5519.


We report a motility in the flagella of the green alga Chlamydomonas that is unrelated to dynein-based flagellar beating. This motility, referred to as intraflagellar transport, was observed as the rapid bidirectional movement of granule-like particles along the length of the flagella. Intraflagellar transport could be experimentally separated from other, previously reported, nonbeat flagellar motilities. EM of flagella showed groups of nonvesicular, lollipop-shaped structures positioned between the outer doublet microtubules and the flagellar membrane. Movement of these complexes along the length of the flagella may be responsible for intraflagellar transport.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Cell Movement
  • Chlamydomonas / physiology*
  • Chlamydomonas / ultrastructure
  • Chlamydomonas reinhardtii / physiology
  • Chlamydomonas reinhardtii / ultrastructure
  • Flagella / physiology*
  • Flagella / ultrastructure
  • Microscopy, Electron
  • Mutation
  • Video Recording