Reproducibility of computed tomography measurement of visceral adipose tissue area

Int J Obes Relat Metab Disord. 1995 Jul;19(7):464-7.


Objective: The purpose of the current study is to examine the reproducibility of CT measurement of the cross-sectional area of abdominal adipose tissue.

Design: Sixteen healthy pre-menopausal women, ranging from lean to obese, underwent duplicate cross-sectional CT scans of the abdomen at the level of the 4th lumbar vertebral disc space. Subjects stood after the initial scan and were then re-positioned prior to repeat CT scanning.

Results: There was a high degree of reproducibility in measurement of overall cross-sectional adipose tissue (AT) and in the partitioning of this into subcutaneous and visceral AT. The excellent reproducibility is demonstrated by a high correlation between duplicate measurements (r = 0.99, P < 0.01), and by small precision errors; 1.2% of the mean value for total AT cross-sectional area, 1.9% for subcutaneous AT area, and 3.9% for visceral AT area.

Conclusion: Measurement of abdominal AT area by cross-sectional CT scanning is not only an accurate determination of this adipose depot but can also be repeated with a high degree of precision.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adipose Tissue / pathology*
  • Adipose Tissue / physiology
  • Adult
  • Female
  • Humans
  • Obesity / pathology
  • Obesity / physiopathology
  • Premenopause
  • Reproducibility of Results
  • Tomography Scanners, X-Ray Computed / standards*
  • Viscera