A steric approach for the design of antihistamines with low muscarinic receptor antagonism

Inflamm Res. 1995 Apr:44 Suppl 1:S90-1. doi: 10.1007/BF01674411.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Butyrophenones / chemistry*
  • Butyrophenones / pharmacology
  • Drug Design*
  • Guinea Pigs
  • Histamine H1 Antagonists / chemistry*
  • Histamine H1 Antagonists / pharmacology
  • In Vitro Techniques
  • Molecular Structure
  • Muscarinic Antagonists / chemistry*
  • Muscarinic Antagonists / pharmacology
  • Piperidines / chemistry*
  • Piperidines / pharmacology
  • Stereoisomerism
  • Structure-Activity Relationship

Substances

  • Butyrophenones
  • Histamine H1 Antagonists
  • Muscarinic Antagonists
  • Piperidines
  • ebastine