Lactococcal bacteriocins: mode of action and immunity

Trends Microbiol. 1995 Aug;3(8):299-304. doi: 10.1016/s0966-842x(00)88958-1.


Bacteriocins are antimicrobial peptides produced by bacteria. Some of those synthesized by Lactococcus lactis have been characterized in great detail recently. The lactococcal bacteriocins are hydrophobic cationic peptides, which form pores in the cytoplasmic membrane of sensitive cells.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Anti-Bacterial Agents / pharmacology
  • Bacteriocins / immunology
  • Bacteriocins / pharmacology*
  • Drug Resistance, Microbial
  • Lactococcus lactis / immunology
  • Lactococcus lactis / physiology*
  • Molecular Sequence Data
  • Nisin / pharmacology


  • Anti-Bacterial Agents
  • Bacteriocins
  • Nisin