Abstract
The iron-regulated promoter involved in desferrioxamine B synthesis of Streptomyces pilosus contains a region homologous to the iron repressor (DtxR)-binding site of the diphtheria toxin gene promoter in Corynebacterium diphtheriae [Günter et al., J. Bacteriol. 175 (1993) 3295-3302]. Here, we report the cloning and sequencing of the putative Streptomyces iron repressor gene, homologous to dtxR of C. diphtheriae. The N-terminal 139 amino acids of the deduced protein are 73% identical to DtxR.
MeSH terms
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Amino Acid Sequence
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Bacterial Proteins / genetics
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Base Sequence
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Cloning, Molecular
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Corynebacterium diphtheriae / genetics
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DNA, Bacterial / genetics
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DNA-Binding Proteins / genetics
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Genes, Bacterial
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Iron / metabolism*
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Molecular Sequence Data
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Repressor Proteins / genetics*
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Sequence Alignment
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Sequence Homology, Amino Acid
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Streptomyces / genetics*
Substances
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Bacterial Proteins
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DNA, Bacterial
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DNA-Binding Proteins
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DtxR protein, Corynebacterium diphtheriae
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Repressor Proteins
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Iron
Associated data
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GENBANK/Z50048
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GENBANK/Z50049