Protein-tyrosine phosphatase SH-PTP2 (PTPN11) is localized to 12q24.1-24.3

Hum Genet. 1995 Nov;96(5):609-15. doi: 10.1007/BF00197421.

Abstract

A 2.1-kb cDNA probe encoding the human SH2-domain containing protein-tyrosine phosphatase SH-PTP2 (PTPN11) was hybridized to human metaphase chromosomes in three independent experiments. In each instance, hybridization was maximal to chromosome 12q24.1-q24.3. The presence of SH-PTP2 cDNA crosshybridizing sequences located on a number of other chromosomes suggested that SH-PTP2-related genes or pseudogenes are present in the human genome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Mapping
  • Chromosomes, Human, Pair 12 / genetics*
  • DNA Probes
  • Humans
  • In Situ Hybridization
  • Intracellular Signaling Peptides and Proteins
  • Protein Tyrosine Phosphatase, Non-Receptor Type 11
  • Protein Tyrosine Phosphatase, Non-Receptor Type 6
  • Protein Tyrosine Phosphatases / genetics*
  • SH2 Domain-Containing Protein Tyrosine Phosphatases

Substances

  • DNA Probes
  • Intracellular Signaling Peptides and Proteins
  • PTPN11 protein, human
  • PTPN6 protein, human
  • Protein Tyrosine Phosphatase, Non-Receptor Type 11
  • Protein Tyrosine Phosphatase, Non-Receptor Type 6
  • Protein Tyrosine Phosphatases
  • SH2 Domain-Containing Protein Tyrosine Phosphatases