Protein-tyrosine phosphatase SH-PTP2 (PTPN11) is localized to 12q24.1-24.3

U Dechert; A M Duncan; L Bastien; C Duff; M Adam; F R Jirik

doi:10.1007/BF00197421

Protein-tyrosine phosphatase SH-PTP2 (PTPN11) is localized to 12q24.1-24.3

Hum Genet. 1995 Nov;96(5):609-15. doi: 10.1007/BF00197421.

Authors

U Dechert¹, A M Duncan, L Bastien, C Duff, M Adam, F R Jirik

Affiliation

¹ Department of Medicine, University of British Columbia, Vancouver, Canada.

PMID: 8530013
DOI: 10.1007/BF00197421

Abstract

A 2.1-kb cDNA probe encoding the human SH2-domain containing protein-tyrosine phosphatase SH-PTP2 (PTPN11) was hybridized to human metaphase chromosomes in three independent experiments. In each instance, hybridization was maximal to chromosome 12q24.1-q24.3. The presence of SH-PTP2 cDNA crosshybridizing sequences located on a number of other chromosomes suggested that SH-PTP2-related genes or pseudogenes are present in the human genome.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromosome Mapping
Chromosomes, Human, Pair 12 / genetics*
DNA Probes
Humans
In Situ Hybridization
Intracellular Signaling Peptides and Proteins
Protein Tyrosine Phosphatase, Non-Receptor Type 11
Protein Tyrosine Phosphatase, Non-Receptor Type 6
Protein Tyrosine Phosphatases / genetics*
SH2 Domain-Containing Protein Tyrosine Phosphatases

Substances

DNA Probes
Intracellular Signaling Peptides and Proteins
PTPN11 protein, human
PTPN6 protein, human
Protein Tyrosine Phosphatase, Non-Receptor Type 11
Protein Tyrosine Phosphatase, Non-Receptor Type 6
Protein Tyrosine Phosphatases
SH2 Domain-Containing Protein Tyrosine Phosphatases