Spontaneous intracranial hypotension from a CSF leak in a patient with Marfan's syndrome

J Neurol Neurosurg Psychiatry. 1995 Nov;59(5):516-9. doi: 10.1136/jnnp.59.5.516.

Abstract

A patient with Marfan's syndrome had spontaneous intracranial hypotension secondary to a proved CSF leak. It is postulated that the leak was caused by minor, unrecognised trauma rupturing spinal arachnoid diverticula. The diverticula were probably pre-existing abnormalities complicating the Marfan's syndrome. It is concluded that patients with spinal meningeal defects may be at increased risk of developing CSF leaks, possibly secondary to unrecognised trauma.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Cerebrospinal Fluid*
  • Female
  • Humans
  • Hypotension, Orthostatic / etiology*
  • Hypotension, Orthostatic / physiopathology
  • Intracranial Pressure
  • Marfan Syndrome / complications*
  • Marfan Syndrome / physiopathology
  • Myelography
  • Subarachnoid Space / diagnostic imaging
  • Tomography, X-Ray Computed