[Sensory ataxic neuropathy associated with Sjögren's syndrome]

Nihon Rinsho. 1995 Oct;53(10):2568-73.
[Article in Japanese]


One tenth of patients with Sjögren's syndrome (SS) is associated with peripheral neuropathy. Trigeminal neuropathy, mononeuropathy multiplex, sensory neuropathy, distal sensory neuropathy, ataxic sensory-autonomic neuropathy have been described as the neuropathy associated with SS. However, some of them secondary occur associated with the vasculopathy due to rheumatoid arthritis, systemic lupus erythematodes etc combined with SS. We demonstrated the clinico-patho-physiological features and spinal MRI findings of patients with primary SS in whom the sensory ataxia and autonomic dysfunctions were the predominant symptoms. The underlying pathology was lymphocytic (T cells) infiltration to the dorsal root ganglia with sensory neuronal degeneration. These findings have identified as association between SS and sensory ataxic neuropathy.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Aged
  • Ataxia / etiology*
  • Autonomic Nervous System Diseases / etiology*
  • Female
  • Ganglia, Spinal / pathology
  • Humans
  • Neurons, Afferent / pathology
  • Sensation Disorders / etiology
  • Sjogren's Syndrome / complications*
  • Sjogren's Syndrome / pathology
  • T-Lymphocytes / pathology