Phialophora verrucosa infection in an AIDS patient

Mycoses. May-Jun 1995;38(5-6):215-8. doi: 10.1111/j.1439-0507.1995.tb00052.x.

Abstract

Phialophora verrucosa is one of several pathogenic dematiaceous fungi associated with chromomycosis and occasionally phaeohyphomycosis. Infection appears to be increasing in frequency in both immunocompromised and presumably healthy patients. Medical therapy is often difficult, and a wide variety of antifungal agents have been tried with varying degrees of success. We report a patient with acquired immunodeficiency syndrome (AIDS) and extensive cutaneous fungal infection due to Phialophora verrucosa. The disease failed to respond to ketoconazole, but regression of the lesions was obtained with itraconazole.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Antifungal Agents / therapeutic use*
  • Dermatomycoses / complications*
  • Dermatomycoses / drug therapy*
  • Elbow / pathology
  • Humans
  • Immunocompromised Host*
  • Itraconazole / therapeutic use*
  • Ketoconazole / therapeutic use
  • Male
  • Phialophora* / cytology
  • Phialophora* / growth & development
  • Pneumonia, Pneumococcal / complications

Substances

  • Antifungal Agents
  • Itraconazole
  • Ketoconazole