Weight, height and human immunodeficiency virus infection in young children of infected mothers. The European Collaborative Study

Pediatr Infect Dis J. 1995 Aug;14(8):685-90.

Abstract

In a longitudinal study of weight and height over the first 4 years of life, 123 human immunodeficiency virus (HIV)-infected and 654 uninfected children of similar social background were compared. By 3 months of age there was a 400-g (8.0%) difference in weight and an 0.8-cm (1.3%) difference in height between infected and uninfected children. After age 1 year the differences stabilized and infected children were, on average, approximately 6% less heavy and 2% shorter than uninfected children. Most of the weight difference was explained by differences in height, particularly after age 1 year. Although statistically significant the difference between infected and uninfected children was small. Weight and height measurements were not useful indicators of infection. Before 6 months of age differences in weight velocity could not be explained by HIV-related morbidity and might have been related to a primary HIV infection. At older ages growth failure associated with HIV infection could be attributed to secondary HIV-related morbidity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Body Height*
  • Body Weight*
  • Child, Preschool
  • HIV Infections / physiopathology*
  • HIV Infections / transmission
  • Humans
  • Infant
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical
  • Longitudinal Studies