Excimer laser photorefractive keratectomy

Surv Ophthalmol. 1995 Sep-Oct;40(2):89-118. doi: 10.1016/s0039-6257(95)80001-8.


Excimer laser photorefractive keratectomy has been used for the correction of myopia, hyperopia and astigmatism. This laser removes tissue through a process termed photoablative decomposition, in which incident photon energy is sufficient to break molecular bonds. Selective removal of tissue across the anterior corneal surface results in a change in anterior corneal curvature. The surgical outcome may be influenced also by interindividual variability in wound healing and pharmacologic interventions. The nature of the excimer laser-tissue interaction, and clinical outcomes of predictability, stability and complications of surgery for myopia are discussed in detail.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Astigmatism / complications
  • Astigmatism / surgery
  • Cornea / physiopathology
  • Cornea / surgery
  • Humans
  • Lasers, Excimer
  • Myopia / complications
  • Myopia / physiopathology
  • Myopia / surgery*
  • Photorefractive Keratectomy*
  • Postoperative Care
  • Preoperative Care
  • Treatment Outcome
  • Visual Acuity