Anti-tumour-promoting glyceroglycolipids from the green alga, Chlorella vulgaris

T Morimoto; A Nagatsu; N Murakami; J Sakakibara; H Tokuda; H Nishino; A Iwashima

doi:10.1016/0031-9422(95)00458-j

Anti-tumour-promoting glyceroglycolipids from the green alga, Chlorella vulgaris

Phytochemistry. 1995 Nov;40(5):1433-7. doi: 10.1016/0031-9422(95)00458-j.

Authors

T Morimoto¹, A Nagatsu, N Murakami, J Sakakibara, H Tokuda, H Nishino, A Iwashima

Affiliation

¹ Faculty of Pharmaceutical Sciences, Nagoya City University, Japan.

PMID: 8534400
DOI: 10.1016/0031-9422(95)00458-j

Abstract

Two new monogalactosyl diacylglycerols were isolated from the freshwater green alga, Chlorella vulgaris, as anti-tumour promoters, together with three monogalactosyl diacylglycerols and two digalactosyl diacylglycerols. The new monogalactosyl diacylglycerol containing (7Z,10Z)-hexadecadienoic acid showed a more potent inhibitory effect toward tumour promotion than the other glycerolipids isolated.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anticarcinogenic Agents / chemistry
Anticarcinogenic Agents / isolation & purification*
Anticarcinogenic Agents / pharmacology*
Carbohydrate Sequence
Chlorella / chemistry*
Drug Screening Assays, Antitumor
Glycerol / chemistry
Glycerol / isolation & purification
Glycerol / pharmacology
Glycolipids / chemistry
Glycolipids / isolation & purification*
Glycolipids / pharmacology*
Humans
Magnetic Resonance Spectroscopy / methods
Molecular Sequence Data

Substances

Anticarcinogenic Agents
Glycolipids
Glycerol