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, 6 (9), 602-6

Characterization and Mapping of a Highly Conserved Processed Pseudogene and an Intron-Carrying Gene of the Heat Shock Cognate Protein 70 (Hsc70) Gene Family in the Rat

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Characterization and Mapping of a Highly Conserved Processed Pseudogene and an Intron-Carrying Gene of the Heat Shock Cognate Protein 70 (Hsc70) Gene Family in the Rat

E Rothermel et al. Mamm Genome.

Abstract

A processed pseudogene of the rat Hsc70 gene, Hsc70-ps1, is described, which still presents the open reading frame of the original gene. The pseudogene does not appear to be expressed. It maps to rat Chromosome (Chr) 2. The intron-carrying Hsc70 gene localizes to Chr 8. Hsc70-specific probes detect a large number of more than 20 cross-hybridizing fragments, which show only limited length polymorphism among various inbred rat strains.

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