Necrotizing sarcoid granulomatosis: computed tomography and pathologic findings

J Comput Assist Tomogr. Nov-Dec 1995;19(6):920-3.

Abstract

Objective: To describe the CT findings and corresponding pathological findings of necrotizing sarcoid granulomatosis (NSG).

Materials and methods: We reviewed the high-resolution CT and macroscopic and histologic findings in three pathologically proven cases of NSG.

Results: The CT findings consisted of one case each with single nodule, multiple nodules, and parenchymal opacification. The abnormalities were peribronchovascular or subpleural in distribution. Histologically, all patients had sarcoid-like granulomas with central necrosis and granulomatous vasculitis. The CT findings correlated closely with the gross pathologic findings.

Conclusion: We conclude that the CT manifestations of NSG reflect the variable macroscopic pathologic findings.

MeSH terms

  • Adult
  • Female
  • Granuloma / diagnostic imaging*
  • Granuloma / pathology*
  • Humans
  • Male
  • Middle Aged
  • Necrosis / pathology
  • Sarcoidosis, Pulmonary / diagnostic imaging*
  • Sarcoidosis, Pulmonary / pathology*
  • Tomography, X-Ray Computed