Pulmonary angiography performed with iopamidol: complications in 1,434 patients

Radiology. 1996 Jan;198(1):61-5. doi: 10.1148/radiology.198.1.8539407.


Purpose: To evaluate the safety of pulmonary angiography performed with iopamidol compared with pulmonary angiography performed with ionic contrast media.

Materials and methods: The data in 1,434 patients who underwent pulmonary angiography with iopamidol 76% were retrospectively reviewed. Complications that occurred within 48 hours were identified with review of hospital charts and/or computer records.

Results: Pulmonary arterial hypertension was present in 402 patients and was severe in 99. Pulmonary embolus was diagnosed in 357 patients (24.9%). Major complications occurred in four patients (0.3%). Respiratory insufficiency occurred in two of these patients. Catheterization was not completed in two patients due to catheter-induced cardiac arrhythmia that was refractory to treatment. No procedure-related deaths occurred. During the periprocedural period, eight patients required intubation and 10 patients died; all patients previously were critically ill.

Conclusion: Pulmonary angiography is a safe procedure, and the margin of safety is enhanced by the use of iopamidol.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Angiography / adverse effects*
  • Catheterization, Swan-Ganz / adverse effects
  • Child
  • Contrast Media / adverse effects*
  • Female
  • Humans
  • Iopamidol / adverse effects*
  • Male
  • Middle Aged
  • Pulmonary Artery / diagnostic imaging*
  • Pulmonary Embolism / diagnostic imaging
  • Retrospective Studies


  • Contrast Media
  • Iopamidol