Identification of amino acid residues of the retroviral aspartic proteinases important for substrate specificity and catalytic efficiency

Adv Exp Med Biol. 1995:362:399-406. doi: 10.1007/978-1-4615-1871-6_52.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Aspartic Acid Endopeptidases / chemistry*
  • Aspartic Acid Endopeptidases / metabolism*
  • Avian Sarcoma Viruses / enzymology*
  • Binding Sites
  • Catalysis
  • Crystallography, X-Ray
  • HIV Protease / chemistry*
  • HIV Protease / metabolism*
  • HIV-1 / enzymology*
  • Humans
  • Kinetics
  • Molecular Sequence Data
  • Mutagenesis, Site-Directed
  • Point Mutation
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / metabolism
  • Substrate Specificity

Substances

  • Recombinant Proteins
  • Aspartic Acid Endopeptidases
  • HIV Protease
  • Rous sarcoma virus protease