Re-creating the RNA world

Curr Biol. 1995 Sep 1;5(9):1017-22. doi: 10.1016/s0960-9822(95)00205-3.

Abstract

Results from in vitro selection experiments can be used to construct and test models for the evolution of the RNA world. Surprisingly, the success of selected RNAs at binding ligands and catalyzing reactions may make it difficult to determine precisely the lineage of molecular fossils, molecules that are believed to have survived from the RNA world to the present.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Evolution, Molecular
  • Models, Biological
  • Origin of Life
  • RNA* / chemistry
  • RNA* / metabolism
  • RNA, Catalytic / metabolism

Substances

  • RNA, Catalytic
  • RNA