Protein folding. Prolyl isomerases join the fold

Curr Biol. 1995 Sep 1;5(9):993-4. doi: 10.1016/s0960-9822(95)00197-7.

Abstract

Cyclophilins have prolyl isomerase activity, but evidence for their suggested role in protein folding in cells has been scarce; now they have been found to accelerate the folding of mitochondrial precursor proteins.

Publication types

  • Review

MeSH terms

  • Amino Acid Isomerases / metabolism*
  • Animals
  • Carrier Proteins / metabolism*
  • Mitochondria / metabolism
  • Peptidylprolyl Isomerase
  • Protein Folding*
  • Protein Precursors / metabolism
  • Tetrahydrofolate Dehydrogenase / metabolism

Substances

  • Carrier Proteins
  • Protein Precursors
  • Tetrahydrofolate Dehydrogenase
  • Amino Acid Isomerases
  • Peptidylprolyl Isomerase